How do I add drug-drug interactions?

Add a co-administered drug icon entering at Stage 3 (Metabolism) and an annotation showing CYP3A4 inhibition slowing metabolism, increasing AUC of the primary drug.

PromptsLife Science

Life ScienceText → ImageMid creditEN

Drug Pharmacokinetics — ADME Diagram

Absorption, Distribution, Metabolism and Excretion summarised with a body schematic and a plasma curve.

When to use this prompt

For pharmacology, medicinal chemistry and clinical-PK figures.

The prompt

An ADME (Absorption, Distribution, Metabolism, Excretion) overview figure.

Left — Body schematic (vertical):
- Stylised human silhouette with key organs labeled.

Four ADME stages annotated as numbered callouts on the body:

1. Absorption — pill icon entering the gastrointestinal tract; absorbed across the intestinal epithelium into the portal vein.
2. Distribution — drug travels via blood to peripheral tissues; show two-compartment idea with central (blood) and peripheral (tissue) compartments connected by reversible arrows.
3. Metabolism — primarily liver (CYP450 enzymes); parent drug -> metabolites; phase I (oxidation) and phase II (conjugation) sub-steps annotated.
4. Excretion — kidneys (urinary) and bile (faecal) routes shown leaving the body.

Right — Plasma concentration vs time curve:
- A clean curve rising to C_max at t_max, then declining exponentially with half-life t_1/2.
- Annotate AUC (area under curve), C_max, t_max and t_1/2.

Style: pharmacology textbook style, restrained palette (slate body, navy for blood, coral for drug), white background, sans-serif labels. Suitable for pharmacology lecture slides and PK / PD reports.

Variations

IV bolus vs oral comparison

Replace the single plasma curve with two curves overlaid: IV bolus (instantaneous C_max, no absorption phase) vs oral (slower rise, lower C_max). Annotate bioavailability F.

Tips

Pair the body schematic with a PK curve. ADME without a curve is incomplete.
Annotate AUC, C_max and t_1/2 directly on the curve, not in a separate caption.
Use distinct routes (urinary vs biliary) for excretion. Single-arrow excretion is too coarse.